Cell-surface Tumoricidal Molecules and NF-κB in the Tumor- burdened Host

……………………………………………………………………………………………..11 INTRODUCTION………………………………………………………………………………..………12 MATERIALS AND METHODS….………………………………...…………………………………...13 RESULTS……………………………………………………………..………………………………...15 Cell-surface expression of mTNF-α, Fas, and FasL on Raw 264.7 cells………..……………….15 Cell-surface expression of mTNF-α, Fas, and FasL on NH and TBH macrophages……………19 Cell-surface expression of Fas and FasL on NH and TBH T-cells……………………..…………25 Cell-surface expression of Fas and FasL on MethKDE tumor cells…………………….…………28 DISCUSSION……………………………………………………………………………………………30 SECTION III: NF-κB IS DYSREGULATED IN TUMOR-BURDENED HOST MACROPHAGES……………………………………………………………………………………....33 ABSTRACT………………………………………………………………...……………………………33………………………………………………………………...……………………………33